Wednesday, November 30, 2011

Blood type - How can AB receive from O?!?

Hello,
I read that AB can receive all blood types.
But how can it receive from O because O have A and B antibodies?
Wouldnt the O's A and B antibodies attack the A and B antigens in the AB recepient blood? Wouldnt it still incentive agglutination - clotting?
Thank you for those who can respond!!
In an emergency situation we can give O packed to the gunwales cells to an AB/A/B being. Most of the anti-A and anti-B antibodies will have be separated off, however some do remain. These are greatly diluted out in the recipient system and so while they may bond to the corresponding A or B antigens they can't all interconnect up forming long chains of antigen/antibody complexes ie the agglutination (that would happen if the concentrations be high). That is why we like to find the recipient blood type ASAP so that we can change the donor unit over to their own blood group.
Only the packed red blood cell would be transfused to the AB person. Since blood group antibodies are within the plasma, which is separated out of the whole blood since transfusion, there won't be any agglutination.
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