1200 mg is considered the maximum daily dose for over-the-counter use, though beneath medical direction, a maximum daily dose of 3200 mg may sometimes be used within increments of 600--800 mg.
Human response in cases of overdose ranges from nothingness of symptoms to fatal outcome surrounded by spite of intensive care treatment. Most symptoms are an excess of the pharmacological dealing of ibuprofen and include abdominal pain, nausea, vomiting, drowsiness, dizziness, headache, tinnitus, and nystagmus. Rarely more severe symptoms such as gastrointestinal bleeding, seizure, metabolic acidosis, hyperkalaemia, hypotension, bradycardia, tachycardia, atrial fibrillation, coma, hepatic dysfunction, acute renal failure, cyanosis, respiratory depression, and cardiac arrest enjoy been reported.[10] The severity of symptoms vary with the ingested dose and the time elapsed, however, individual sensitivity also plays an meaningful role. Generally, the symptoms observed with an overdose of ibuprofen are similar to the symptoms cause by overdoses of other NSAIDs.
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